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Hey there! Today we are going to talk about alpha, beta-unsaturated ketones. You might be wondering, what exactly is an alpha, beta-unsaturated ketone? Well, let’s dive in and find out. An alpha, beta-unsaturated ketone is a type of organic compound that contains a carbonyl group (a carbon atom double-bonded to an oxygen atom) and an unsaturated carbon-carbon bond. This double bond is located on the alpha (α) and beta (β) carbon atoms, hence the name. Now, you might be thinking, what’s the big deal about alpha, beta-unsaturated ketones? Well, these compounds have some unique properties that make them interesting to study. One such property is their ability to undergo a reaction called the Robinson annulation. The Robinson annulation is a reaction in which an alpha, beta-unsaturated ketone reacts with a ketone or aldehyde to form a cyclic compound. This reaction is named after Sir Robert Robinson, who first described it in 1935. To give you an example, let’s take a look at the following alpha, beta-unsaturated ketone:
Example:
This is an example of an alpha, beta-unsaturated ketone. Notice the carbon-carbon double bond on the alpha and beta carbon atoms.
When this alpha, beta-unsaturated ketone reacts with an aldehyde, it undergoes the Robinson annulation to form a cyclic compound: Robinson Annulation:

When an alpha, beta-unsaturated ketone reacts with an aldehyde, it undergoes the Robinson annulation to form a cyclic compound.
Now, you might be wondering, why do alpha, beta-unsaturated ketones undergo the Robinson annulation in the first place? Well, it all has to do with the stabilization of the double bond. The cyclic compound that is formed is more stable than the starting alpha, beta-unsaturated ketone because it has a conjugated system of double bonds. In conclusion, alpha, beta-unsaturated ketones are a fascinating type of organic compound that have some unique properties, such as their ability to undergo the Robinson annulation. Studying these compounds is important for understanding the fundamentals of organic chemistry and for developing new synthetic routes to complex molecules. Thanks for joining me today, and I hope you learned something new! If you are looking for What is an alpha, beta-unsaturated ketone? + Example you’ve visit to the right place. We have 5 Pics about What is an alpha, beta-unsaturated ketone? + Example like What is Ketosis? The Science Explained. | Peter Attia M.D., Why Keto Salts Are the Most Reliable Keto Supplement and also Ketone Salts: Ketosis with a Cost | H.V.M.N. Blog. Here you go:
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